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Anti-CD40LG Antibody Fab (CAT#: MOM-18027-F(P))

Datasheet
DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human CD40LG Antibody Fab Fragment MOM-18027-F(P) 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant Humanized (from mouse) Antibody Fab Fragment specifically binds to Human CD40L, expressed in E. coli
  • Target
  • CD40L
  • Type
  • Fab Fragment based on Humanized (from mouse) IgG1 - kappa
  • Immunogen
  • Animals were immunized with D1.1 cells.
  • Species Reactivity
  • Human
  • Expression Host
  • E. coli
  • Applications
  • Suitable for use in FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.
  • Specific Activity
  • Tested positive against native antigen.
  • Purity
  • >97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
  • Storage
  • At -20°C for one year.

BACKGROUND

  • Antigen Description
  • Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of IL-4. Involved in immunoglobulin class switching. Release of soluble CD40L from platelets is partially regulated by GP IIb/IIIa, actin polymerization, and an matrix metalloproteinases (MMP) inhibitor-sensitive pathway.
  • Function
  • CD40 receptor binding; cytokine activity; tumor necrosis factor receptor binding;
  • Keywords
  • 0
  • Synonyms
  • CD40LG; CD40 ligand; HIGM1, IMD3, TNFSF5, tumor necrosis factor (ligand) superfamily, member 5 (hyper IgM syndrome); CD40 antigen ligand; CD40L; CD154; gp39; hCD40L; hyper IgM syndrome; T B cell activating molecule; TNF related activation protein; TRAP; tumor necrosis factor (ligand) superfamily member 5; CD40-L; T-cell antigen Gp39; T-B cell-activating molecule; TNF-related activation protein; IGM; IMD3; HIGM1; T-BAM; TNFSF5;

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